Molecular Mechanisms of Cancer Metabolism and Their Cellular Cycles

Cancer is a prevalent disease, with 1,752,735 new cases reported to the CDC in 2019. The disease characterized by uncontrolled growth and spread of abnormal cells. Current treatments for cancer can affect whole body have detrimental effects. cells are often programmed metabolically. In recent years, undermine this metabolic reprogramming come forefront. review, we explore some molecular mechanisms underlying certain dietary interventions critical pathways. Dietary such as chronic calorie restriction (CR) fasting been shown aid adjusting help reducing progression. Other target amino acid (AA) metabolism. Essential AAs only consumed from diet their has work treatment mice. Lastly, central carbon metabolism includes TCA cycle glycolysis, both commonly reprogrammed pathways these be used treat other ways, knocking out genes cell arrest.